Scientists funded by Cancer Research UK have discovered dementia-like behavior in pancreatic cells that are at risk of becoming cancerous. The findings provide clues that could help in the treatment and prevention of pancreatic cancer, a difficult-to-treat disease that is responsible for 6,900 deaths in the UK each year. Approximately 495,000 new cases are diagnosed […]
Can Circadian Disorders Accelerate the Progression of Colorectal Cancer?
A study by the University of California, Irvine, has shown how disruption of the circadian clock, the body’s own 24-hour biological pacemaker, can accelerate the progression of colorectal cancer by impairing the intestinal microbiome and intestinal barrier function. This discovery offers new opportunities for prevention and treatment strategies. The study, published in the journal Science […]
Circadian Rhythms can Influence the Effectiveness of Medication
Using tiny engineered liver organs derived from human donor cells, researchers found that many genes involved in drug metabolism are under circadian control. These circadian fluctuations affect how much of a drug is available and how effectively the body can break it down. For example, they found that enzymes that break down Tylenol and other […]
Biological Network in Cells and the Development of Diseases
There are more than 200 different cell types in the human body. Each cell is specialized to perform a specific function or form a specialized tissue. When cells don’t function properly, different diseases can occur. Scientists have now conducted research that opens up a whole new world inside our cells. Every minute of every day, […]
Immune Response to Vaccination: The Role of the Circadian Rhythm
Many physiological and behavioral functions, including the immune system, exhibit circadian rhythms. We know that circadian rhythms are generated by “clock genes” that affect most organs and cells – including those of the immune system, whose function varies with the time of day. Accordingly, circadian rhythms are found for various aspects of physiology, including sleep, […]
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