By separating the therapeutic benefits from the adverse effects of known obesity drugs, researchers at the Monell Chemical Senses Center found a population of neurons in the brain that controls food intake without causing nausea in animal models. The study, published in the journal Nature, describes two distinct neural circuits that control different effects of […]
Hepatitis B: “Sleep Timer” for Immune Cells Discovered
In chronic hepatitis B, the liver contains immune cells that could destroy cells infected with the hepatitis B virus, but are inactive. A team at the Technical University of Munich (TUM) has discovered that cells in the blood vessels of the liver set off a “sleep timer” that switches off the immune cells. An attack […]
Inflammation in Young Adulthood Has an Impact on Mental Health
Higher levels of inflammation in young adulthood are linked to lower performance on skills tests in midlife. Young adults with elevated levels of inflammation associated with obesity, physical inactivity, chronic disease, stress and smoking may have lower cognitive performance in midlife, a new UC San Francisco study shows. Researchers had previously linked higher levels of […]
Researchers Identify Promising Proteins for the Treatment of Metabolic Diseases
A University of Saskatchewan (USask) research team’s discovery of the additional health benefits of an appetite-suppressing protein has doubled the potential for scientists to find new ways to treat obesity and metabolic disorders in animals and humans. The researchers’ findings, recently published in the journal Nature Communications Biology, highlight their discovery of the lipid-lowering effects […]
Circadian Rhythms can Influence the Effectiveness of Medication
Using tiny engineered liver organs derived from human donor cells, researchers found that many genes involved in drug metabolism are under circadian control. These circadian fluctuations affect how much of a drug is available and how effectively the body can break it down. For example, they found that enzymes that break down Tylenol and other […]
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